News & articles

April 2011 The Belgian Journal of Hematology recently published their review of the state of JAK Inhibitors. Since its discovery in 2005 several companies have been working on creating a JAK Inhibitor for treatment of the myeloproliferative neoplasms. Click here to read the full article (PDF) Current trials for polycythemia vera, essential thrombocythemia and myelofibrosis… Read More »EUROPEAN JOURNAL OFFERS REVIEW OF CURRENT JAK INHIBITORS

March 2011 The patients who run the MPD Foundation are impatient to see results from the medical research they fund. That’s understandable: their rare blood diseases – essential thrombocythemia, polycythemia vera and myelofibrosis, collectively called myeloproliferative neoplasms – are progressive, incurable and generally not well managed by existing medicines. So, in its latest round of… Read More »PATIENTS PUSH RESEARCHERS TO SHARE DATA

February 2011 The MPN Research Foundation (formerly MPD Foundation) is pleased to announce the recipients of its Established Investigator and New Investigator grants for 2011. These awards follow an extensive proposal review process conducted by the MPN Research Foundation’s Scientific Advisory Board as well as additional MPN experts who gave generously of their time and… Read More »2011 MPN RESEARCH FOUNDATION

January 2011 Geron Corporation has enrolled their first person in a Phase 2 clinical trial to test their drug (GRN163L) in patients with essential thrombocythemia. These drugs are aiming to target the leukemic stem cell, which Geron believes will “impact the biology of the disease”. This Phase 2 trial is testing the safety and efficacy… Read More »GERON ENROLLS FIRST PATIENT IN DRUG STUDY FOR ESSENTIAL THROMBOCYTHEMIA

December 2010 Incyte Corp. is currently working on phase II clinical trials for their JAK Inhibitor INCB18424. These trials are testing safety and efficacy of this drug, meant to relieve constitutional symptoms in ET and PV patients. Results were reported at the American Society of Hematology’s annual meeting. Click here for more information

December 2010 Data from SBio’s ongoing clinical trial for their JAK2 Inhibitor SB1518 was reported at the recent annual meeting of the American Society of Hematology. Dr. Srdan Verstovsek reported that thus far 57% of patients enrolled had experience reduction in spleen as well as reduction in constitutional symptoms of myelofibrosis. The drug was reported… Read More »SBIO DRUG SHOWS PROMISE FOR SYMPTOM AND SPLEEN REDUCTION FOR MYELOFIBROSIS PATIENTS

November 2010By Ann Brazeau The MPD Foundation hosted a patient educational symposium in San Diego on October 25, 2010 at the UCSD Moores Cancer Center in La Jolla. Each speaker commended the attendees for taking an active role in learning about their rare blood cancer and for supporting research and awareness efforts to ensure better… Read More »MPN RESEARCH FOUNDATION’S SAN DIEGO SYMPOSIUM BRINGS THE EXPERTS TO THE PATIENTS

October 2010 Click here to read about a New Jersey MF patient and her struggle with MF.

October 2010 By Zhenya Senyak Eileen Wiggins – Out of the blue Eileen Wiggins is a practical woman, straightforward, no nonsense. So when she started feeling tired most all the time and losing a little weight – not that she couldn’t afford to drop a few pounds here and there but for her age she… Read More »WHITE PAPER: NATURE, NURTURE, OR BOTH?

October 2010 SBio, based in Singapore, is working on a JAK2 Inhibitor for Myelofibrosis patients, SB1518. They have just been granted orphan drug designation from the European Commission. The European Commission is the executive body of the European Union, and has an orphan drug incentive program similar to the U.S. This development potentially expands the… Read More »SBIO GRANTED ORPHAN DESIGNATION FOR MYELOFIBROSIS DRUG