News & articles

What GLP-1 drugs reveal about MPNs, inflammation, and cancer risk A surprising link between inflammation, clonal blood stem cells, and a blockbuster drug opens new questions in blood cancer research. In recent years, glucagon-like peptide-1 receptor agonists (GLP-1RAs) — the class of drugs that includes Ozempic, Wegovy, and others — transformed care for type 2… Read More »What GLP-1 Drugs Reveal About MPNs, Inflammation, and Cancer Risk 

What do megakaryocytes, machine learning, and a team of Oxford scientists have in common? They’re all part of Dr. Daniel Royston’s mission to teach computers how to see what pathologists might miss — the secret signs of fibrosis hiding in the bone marrow. In this month’s Researcher Spotlight, step inside a one-of-a-kind laboratory where engineers… Read More »How to train your AI model: Dr. Daniel Royston’s quest to decode the bone marrow 

Explaining a chronic cancer like an MPN to a child can feel overwhelming — especially when the symptoms aren’t always visible. In this new article, pediatric psychologist Dr. Joanna Patten shares expert advice on what to say and how to say it. Learn why late is better than never and how honest, age-appropriate conversations help… Read More »How to explain MPNs to children

At the center of translational research, clinical care, and academic leadership, Dr. Gabriela Hobbs, MD is charting a more thoughtful path forward for people living with MPNs. Through collaboration and leadership, she’s transforming every resource into scientific discoveries.  “Research can look different in a lot of ways,” Dr. Gabriela Hobbs says with a knowing nod.… Read More »Every sample, every step: How Dr. Gabriela Hobbs is rethinking the transplant journey in MPNs 

MPN Pathways: Empowered Voices in Research bonus session — What’s your why? At MPN Research Foundation, we are dedicated to ensuring that the patient’s voice is at the forefront of our work. As we grow in our role as a patient-centered research foundation, we continue to take intentional steps to bridge the intersection of patients,… Read More »MPN Pathways: Empowered Voices in Research Bonus Session Summary — What’s Your Why?

Profile: Brandi Reeves, MDUniversity of North Caroline at Chapel Hill Hematologist discovers the kidneys: One researcher’s quest to explain an overlooked MPN complication   It all started with a series of patients who couldn’t qualify for a clinical trial. Not for lack of interest — one after another, patients with myeloproliferative neoplasms (MPNs) couldn’t meet enrollment criteria.… Read More »Hematologist discovers the kidneys: One researcher’s quest to explain an overlooked MPN complication  

Profile: Simón Méndez-Ferrer, PhDRutgers University Beyond mutant cells: Dr. Simón Méndez-Ferrer on the role of the bone marrow environment in myelofibrosis (MF). In a healthy body, the bone marrow is a bustling ecosystem, teeming with diverse cellular species, each playing a supportive role and maintaining balance. Stem cells stand at the heart of this environment,… Read More »Dr. Simón Méndez-Ferrer Research Profile

MPN Research Foundation (MPNRF) and Canadian MPN Research Foundation (CMPNRF) launch collaboration to improve outcomes for MPN patients. MPN Research Foundation and Canadian MPN Research Foundation are pleased to announce a new collaboration focused on improving outcomes for myeloproliferative neoplasm (MPN) patients in the U.S., Canada, and beyond. The goal of the strategic initiative is… Read More »MPN Research Foundation (MPNRF) and Canadian MPN Research Foundation (CMPNRF) launch collaboration to improve outcomes for MPN patients

Trouble in the neighborhood: How one type of chromosome abnormality is more common than previously thought A recent study by Dr. Vesna Najfeld and her team brings fresh insights into myelofibrosis (MF), a type of myeloproliferative neoplasm (MPN). Their work highlights the importance of closely tracking genetic changes over time and suggests that changes around… Read More »Trouble in the neighborhood: How one type of chromosome abnormality is more common than previously thought

A wedding with a cause: How Adam and Jenny transformed tradition into purpose When Jenny Applequist was diagnosed with a myeloproliferative neoplasm (MPN) in 2019, it marked the beginning of a transformative journey. “I felt a flood of emotions when I was first diagnosed,” Jenny shared. “I was still in denial for years.” Over time,… Read More »A wedding with a cause: How Adam and Jenny transformed tradition into purpose